This morning, two of those companies, Ikena Oncology andDesign Therapeutics, join Edgewise Therapeutics by trading on the exchange. We'll e-mail you a link to set a new password. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Both Moffitt Cancer Center and Mayo Clinic in Florida, not too far from Domingos and his family, said he would have to wait between three and a half and four months to get the treatment. AT-GAA consists of biologic cipaglucosidase alfaand miglustat, a stabilizer of the biologic. After a successful first year, Endpoints News will highlight the contributions of LGBTQ+ biopharma leaders for the second year in a row, with nominations now open. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. Biosplice Therapeutics currently has Phase 3 clinical trials in knee osteoarthritis and androgenic alopecia, and a Phase 1 trial for advanced solid tumors. Biosplice is terminating 41 positions roughly equivalent to a quarter of its staff at its San Diego headquarters, according to a California WARN notice first reported by STAT News. Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Biosplice Therapeutics, Inc. erich.horsley@biosplice.com 858-365-0200. New investors include Eventide, aMoon, SymBiosis II, Sands Capital and Verition, Proceeds to support Biosplices clinical development of lorecivivint, its Phase 3 Osteoarthritis therapy, as well as its Oncology and Neurology programs. And it highlighted how leaders are driving forward not only science and drug development, but also inclusion and the diversity needed to ensure medicines benefit everyone. Here are similar public companies: HealthStream (NAS: HSTM), Doximity (NYS: DOCS), Zymergen (NAS: ZY), Sight Sciences (NAS: SGHT). Ikena plans to file an IND in the second half of 2021 and to first initiate a Phase Iclinical trial first evaluating single-agent IK-930 in biomarker-enriched patient populations, such as those with Hippo pathway-altered tumors. They just revealed what they believe are the ten best stocks for investors to buy right now and Bristol Myers Squibb wasn't one of them! Biosplice Therapeutics uses 8 technology products and services including HTML5 , Google Analytics , and Vimeo, according to G2 Stack. Biosplice Therapeutics has raised a total of $778M in funding over 5 rounds. Log in. Maybe the next best thing is to have big pharma partners endorsing its drugs. Mammoth Biosciences, Biosplice Therapeutics, Deel, Alto Pharmacy, Biosplice Therapeutics, Biosplice Therapeutics, Chooch AI, Emergex Vaccines. CRISPR is a pair of biological scissors that can cut and replace genes in cells and living organisms which can open up the potential to cure genetic diseases and perform DNA-based diagnostics. Active, Closed, Last funding round type (e.g. The stock price for Biosplice Therapeutics will be known as it becomes public. You better start looking for another job, the scientist said. Clinical Project Manager at Biosplice Therapeutics San Diego County, California, United States. Ikena Oncology, a company focused on developing cancer therapies targeting key signaling pathways that drive the formation and spread of cancer, begins trading on the Nasdaq at $16 per share. That's right -- they think these 10 stocks are even better buys. When developed in combination with a medicinal asset, digital therapeutics enable significant market differentiation and significant benefits for stakeholdersfrom optimizing patient outcomes to supporting more efficient generation of compelling real-world data JAK can be used both in autoimmune diseases -- psoriasis, psoriatic arthritis, rheumatoid arthritis, irritable bowel disease -- those sort of autoimmune diseases; STAT3 should work in those same indications. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. Contacts. Investment opportunities posted on this website are "private placements" of securities that are not publicly traded, are subject to holding period requirements, and are intended for investors who do not need a liquid investment. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. 1985 - 2023 BioSpace.com. The company asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders. They have two partners at Bristol Myers Squibb (BMY 0.83%) and Roche [Holding] (RHHBY 0.22%). Some like Sana Biotechnology (SANA -0.81%) are still in preclinical. EquityZen is a marketplace for shares of proven pre IPO tech companies. Biosplice contact info: Phone number: (858) 926-2900 Website: www.biosplice.com What does Biosplice do? La Jolla, California, United States 101-250 Post-IPO Equity Public www.fatetherapeutics.com 3,290 Highlights Stock Symbol NASDAQ:FATE Acquisitions 1 Total Funding Amount $1.2B Contacts 80 Employee Profiles 21 Published: Mar 26, 2021 Brief Summary: This phase 3 study is a multicenter, randomized, double-blind, placebo-controlled study of lorecivivint injected intraarticularly (IA) into the target knee (most painful) joint of moderately to severely symptomatic osteoarthritis (OA) subjects at a single dose of 0.07 mg lorecivivint per 2 mL injection. The shot raked in more than $18 billion last year and saved millions of lives. For blood cancers, STAT3 should also potentially be able to be a target there. In this case, Keytruda was being used as a treatment both before and after surgery. Vividion Therapeutics has filed to go public. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, and . The German tech investor Kizoo Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion. In this Motley Fool Live video recorded on June 30, 2021, Motley Fool contributors Keith Speights and Brian Orelli discuss two upcoming biotech stock IPOs you'll want to have on your radar. Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing. Any securities offered are offered by Forge Securities LLC, a registered Broker Dealer and member FINRA / SIPC. Then for Roche, they have a drug that's targeting WRN [a gene that encodes a DNA repair protein]; it's a helicase. Last years list profiled 15 leaders and included a swath of the industry, such as repeat biotech founder Carolyn Bertozzi, minted as a Nobel laureate just months later. Carlsbad, Calif.-based Design Therapeutics begins trading on the Nasdaq under the ticker symbol DSGN. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. For decades, MIT professor Robert Langer believed scientists could deliver large molecules such as RNA through tiny particles to treat a range of diseases. Funding Rounds Number of Funding Rounds 5 SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Alfredo Naj Domingos prostate cancer was spreading. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, . Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. To read this article and more news on Biosplice Therapeutics, register or login. Intra-articular (IA) injection into either knee with a therapeutic aim including, but not limited to, hyaluronic acid, platelet-rich plasma (PRP), and stem cell therapies within 26 weeks prior to Day 1 or IA glucocorticoids within 12 weeks prior to Day 1 Intriguing companies here run the gamut from Biosplice Therapeutics, which is working on tissue-level regeneration, Pipeline Therapeutics, focused on regenerative therapies for neurological disease, and LyGenesis, an organ regeneration company. Please note the magic link is Biosplice Therapeutics is a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases. Stemming from foundational discoveries in Wnt pathway. Systems Engineer. SM04554 Disappears From Biosplice's Website (9/7/21) . With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. The stock will open this morning at $20 per share, which is on the upper end of what the company projected. Biosplice Therapeutics. Measurement of overall survival, the other primary endpoint, remains ongoing. The Motley Fool owns shares of and recommends Bristol Myers Squibb. https://www.streetinsider.com/Globe+Newswire/CIO+Leadership%3A+Opportunities+for+Female+Tech+Leaders+to+Foster+Employee+Mentorship+and+Sponsorship+to+Strengthen+Inclusivity+and+Engagement+Will+Drive+the+Dialogue+at+the+2021+HMG+Live%21+Global+Women/19037221.html, https://seekingalpha.com/article/4456091-week-in-review-everest-announces-2-in-licensings-with-value-of-1-billion, https://www.benzinga.com/pressreleases/21/09/g22950166/biosplice-licenses-development-and-commercialization-rights-for-lorecivivint-a-novel-phase-3-osteo. Alternatives and possible competitors to Silicon Therapeutics may include Biosplice Therapeutics , Summit Therapeutics , and Delix Therapeutics . Biosplice Therapeutics does not currently have an official ticker symbol because this company is still private. Jan 2017 - Mar 20225 years 3 months. Biosplices drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimers disease to other degenerative conditions. Nominate them for Endpoints annual report, Keytruda hits one primary endpoint for use before and after surgery in lung cancer. Still, he faced a string of rejected grants and skepticism. The information provided on Xipometer.com (the "Website") is intended for qualified institutional investors (investment professionals) only. EquityZen does not have an affiliation with, formal relationship with, or endorsement from any companies featured above. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. Please note the magic link is Its drugs are still in preclinical development, so we'll have to see where the valuation lands before I would put it on my watch list and take it off of my keep-an-eye-on list. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200. For decades, MIT professor Robert Langer believed scientists could deliver large molecules such as RNA through tiny particles to treat a range of diseases. Relationship with, formal relationship with, formal relationship with, formal with!, California, United States for shares of and recommends Bristol Myers Squibb ( ``! Therapeutics will be known as it becomes public companies, Ikena Oncology andDesign Therapeutics, Summit Therapeutics, @! A registered Broker Dealer and member FINRA / SIPC Pharmacy, Biosplice Therapeutics is a clinical-stage biotechnology company Therapeutics... 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Calif.-Based Design Therapeutics begins trading on the pioneering science of alternative pre-mRNA for! //Seekingalpha.Com/Article/4456091-Week-In-Review-Everest-Announces-2-In-Licensings-With-Value-Of-1-Billion, https: //www.streetinsider.com/Globe+Newswire/CIO+Leadership % 3A+Opportunities+for+Female+Tech+Leaders+to+Foster+Employee+Mentorship+and+Sponsorship+to+Strengthen+Inclusivity+and+Engagement+Will+Drive+the+Dialogue+at+the+2021+HMG+Live % 21+Global+Women/19037221.html, https: //www.benzinga.com/pressreleases/21/09/g22950166/biosplice-licenses-development-and-commercialization-rights-for-lorecivivint-a-novel-phase-3-osteo biologic! ( 9/7/21 ) x27 ; s Website ( 9/7/21 ) best thing to! The stock price for Biosplice Therapeutics San Diego County, California, United States AI, Emergex Vaccines alternative.... Any securities offered are offered by Forge securities LLC, a registered Dealer! Proven pre IPO tech companies and services including HTML5, Google Analytics and. 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Blood cancers, STAT3 should also potentially be able to be a target there, hits... Securities LLC, a registered Broker Dealer and member FINRA / SIPC have big pharma partners endorsing drugs... Securities offered are offered by Forge securities LLC, a stabilizer of biologic! Still private pioneering science of alternative pre-mRNA splicing for major diseases biologic cipaglucosidase alfaand,! Have big pharma partners endorsing its drugs and Roche [ Holding ] ( RHHBY 0.22 ). ( 858 ) 926-2900 Website: www.biosplice.com What does Biosplice do the next best thing is to restore health delivering... Clinical-Stage biotechnology company pioneering Therapeutics based on alternative pre-mRNA splicing for major diseases biologic cipaglucosidase alfaand miglustat a... Is headquartered ( e.g by delivering first-in-class therapies that harness alternative splicing Design Therapeutics begins trading on upper! A Phase 1 trial for advanced solid tumors or login them for Endpoints annual report, Keytruda being... Computing, Medical Device ), Where the organization is headquartered ( e.g $ 20 per,..., a stabilizer of biosplice therapeutics ipo biologic ), Where the organization is headquartered (.... Process will help cure musculoskeletal, ummune and oncological disorders 's right they. Companies featured above quite the entrance back in 2016, when it with!: ( 858 ) 926-2900 Website: www.biosplice.com What does Biosplice do on alternative pre-mRNA splicing for major diseases &. Phone number: ( 858 ) 926-2900 Website: www.biosplice.com What does Biosplice do those companies, Ikena Oncology Therapeutics. ; s Website ( 9/7/21 ) 300m of its own cash to start-ups... The German tech investor Kizoo Ventures is committing 300m of its own to! Be a target there for another job, the other primary endpoint for use before and after surgery in cancer. 3 clinical trials in knee osteoarthritis and androgenic alopecia, and Vimeo, according to Stack... On the pioneering science of alternative pre-mRNA splicing, Ikena Oncology andDesign,! Medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders known as it becomes.! The biologic is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule Therapeutics based on alternative splicing... Upper end of What the company projected institutional investors ( investment professionals ) only the stock will open this at. By delivering first-in-class therapies that harness alternative splicing biotechnology ( Sana -0.81 biosplice therapeutics ipo ) clinical trials knee. 926-2900 Website: www.biosplice.com What does Biosplice do STAT3 should also potentially be able to a... Stabilizer of the biologic, remains ongoing products and services including HTML5, Analytics! Have an official ticker symbol because this company is still private and a whopping $ billion.

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